Handle with Care: A Novel


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(as of Dec 06, 2025 12:52:13 UTC – Details)


When Willow is born with severe osteogenesis imperfecta, her parents are devastated—she will suffer hundreds of broken bones as she grows, a lifetime of pain. In this provocative story from the #1 New York Times bestselling author, “Picoult writes with unassuming brilliance” (Stephen King).

Every expectant parent insists the same thing: they simply want a healthy baby. Charlotte and Sean O’Keefe wanted the same but instead, their lives are made up of sleepless nights, mounting bills, pity from other parents, and haunting what-ifs.

Yet, in other ways, their daughter Willow is a perfect child. Smart as a whip, beautiful, brave, and kind, Willow is Willow, in sickness and in health.

Everything changes, though, after a series of events forces Charlotte and Sean to confront the most serious what-ifs of all. What if Charlotte had known earlier of Willow’s illness? What if things could have been different? What if their beloved Willow had never been born? To do Willow justice, Charlotte must ask herself these questions and one more: what constitutes a valuable life?

“Well-written and conscientiously researched” (The Washington Post), Handle with Care is an unforgettable and emotionally riveting novel that explores the fragility of life and the lengths we go to protect it.

ASIN ‏ : ‎ B001NLKSYI
Publisher ‏ : ‎ Atria Books
Accessibility ‏ : ‎ Learn more
Publication date ‏ : ‎ February 20, 2009
Language ‏ : ‎ English
File size ‏ : ‎ 2.3 MB
Screen Reader ‏ : ‎ Supported
Enhanced typesetting ‏ : ‎ Enabled
X-Ray ‏ : ‎ Enabled
Word Wise ‏ : ‎ Enabled
Print length ‏ : ‎ 497 pages
ISBN-13 ‏ : ‎ 978-1439156308
Page Flip ‏ : ‎ Enabled
Best Sellers Rank: #15,815 in Kindle Store (See Top 100 in Kindle Store) #152 in Contemporary Literary Fiction #175 in Women’s Literary Fiction #196 in Sisters Fiction
Customer Reviews: 4.4 4.4 out of 5 stars (6,225) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });

Customers say

Customers find the book a quick yet thoughtful read with excellent writing in Picoult’s signature style, and appreciate how it keeps them engaged from start to finish. They praise the character development, particularly how each chapter is told from another character’s perspective, and consider it thought-provoking, with one customer noting how it reflects on important life aspects. The story receives mixed reactions, with some finding it excellent while others describe it as gut-wrenching.

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